Liu Y C, Chen R J, Chang D Y, Huang S C, Chow S N
Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1996 Oct;58(4):294-8.
Adenocarcinoma in situ (AIS) of the uterine cervix is a rare disease. Some authors suggested that conization is a suitable treatment for AIS as for squamous cell carcinoma in situ. However, others did not agree. Four cases of AIS, from 1984 to 1994, have been diagnosed in the Hospital of National Taiwan University. If the diagnosis of the conization specimen showed AIS, abdominal total hysterectomy was performed days thereafter. The remaining uterine cervix was checked by histopathology to determine whether it was free of cancer lesions. AIS lesions remained in the uterine cervix, as shown by conization in two cases. AIS is not like lesion as squamous cell carcinoma in situ lesion which is easy to be removed by conization. It is suggested that conization is not an adequate treatment for AIS, rather, a total hysterectomy should be performed.
子宫颈原位腺癌（AIS）是一种罕见疾病。一些作者认为，对于AIS，锥形切除术是一种如同针对原位鳞状细胞癌一样合适的治疗方法。然而，其他作者并不认同。1984年至1994年间，台湾大学医院诊断出4例AIS。如果锥形切除标本的诊断显示为AIS，随后数天会进行腹式全子宫切除术。对剩余的子宫颈进行组织病理学检查，以确定是否无癌性病变。如锥形切除所示，2例患者的子宫颈中仍存在AIS病变。AIS不像原位鳞状细胞癌病变那样容易通过锥形切除术切除。建议锥形切除术并非AIS的充分治疗方法，相反，应进行全子宫切除术。
