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[肿瘤细胞和非肿瘤细胞分泌改变巨噬细胞迁移的物质以及免疫淋巴细胞在体外的细胞致病作用]

[Secretion by tumor and non-tumor cells of substances modifying macrophage migration and the cytopathogenic effect of immune lymphocytes in vitro].

作者信息

Razvorotnev V A, Lavrovskiĭ V A, Viksler V Kh

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977 Jun(6):48-51.

PMID:899434
Abstract

Tumour cells were shown to secrete substances stimulating macrophage migration in vitro and also those depressing the cytopathogenic action of immune lymphocytes in vitro. Embryo fibroblasts (examined in paralled as nontumour cells) secreted as did tumour cells, substances stimulating the macrophage migration, but not substances capable of depressing the cytopathogenic action of immune lymphocytes. L-cells secreted substances inhibiting macrophage migration, but failed to secrete substances depressing the cytopathogenic action of immune lymphocytes.

摘要

肿瘤细胞在体外可分泌刺激巨噬细胞迁移的物质,也可分泌抑制免疫淋巴细胞细胞致病作用的物质。胚胎成纤维细胞(作为非肿瘤细胞进行平行检测)与肿瘤细胞一样,可分泌刺激巨噬细胞迁移的物质,但不能分泌抑制免疫淋巴细胞细胞致病作用的物质。L细胞分泌抑制巨噬细胞迁移的物质,但不能分泌抑制免疫淋巴细胞细胞致病作用的物质。

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