Havukkala I J
Genesis Research & Development Ltd, Auckland, New Zealand.
Curr Opin Genet Dev. 1996 Dec;6(6):711-4. doi: 10.1016/s0959-437x(96)80025-6.
Researchers are eagerly waiting for the physical map of rice to become completed and available for use as a model for all cereals. The most significant advances of the past year have been the progress toward positional cloning of genes and the identification of quantitative trait loci (QTL) from detailed restriction fragment length polymorphism maps. Future focus will be: first, the enhanced dissemination and integration of the available data in World Wide Web accessible databases for easy comparison of genetic and physical mapping data across various species; second, the expanded distribution of a wide variety of DNA materials (cDNA clones, yeast artificial chromosomes, bacterial artificial chromosomes and other probes) for use in other cereals on the basis of the rice model map; and third, the applied breeding by locating and isolating sequences corresponding to important agronomic traits, often correlating with QTL.
研究人员正急切地等待水稻物理图谱的完成,并将其用作所有谷物的模型。过去一年最重要的进展是在基因的定位克隆方面取得了进展,并从详细的限制性片段长度多态性图谱中鉴定出数量性状基因座(QTL)。未来的重点将是:第一,加强在万维网可访问数据库中现有数据的传播和整合,以便轻松比较不同物种的遗传图谱和物理图谱数据;第二,基于水稻模型图谱,扩大各种DNA材料(cDNA克隆、酵母人工染色体、细菌人工染色体和其他探针)在其他谷物中的分布;第三,通过定位和分离与重要农艺性状相对应的序列(通常与QTL相关)进行应用育种。