The role of recombinant human growth hormone (rhGH) in pubertal patients.

Growth response to rhGH decreases with increasing age. Transplanted adolescents, however, respond to rhGH in a comparable way to that of younger children. Caution should be used in transplanted children who, in our experience, grow as well as younger children. Whether or not the use of rhGH improves final height if used during puberty remains unknown.