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腹膜透析患者对重组人生长激素(rhGH)的反应是否比慢性肾功能不全患者更无效?

Is the response to rhGH in peritoneal dialysis patients less effective than in patients with chronic renal insufficiency.

作者信息

Perfumo F, Verrina E, Edefonti A, Trivelli A, Canepa A, Gusmano R

机构信息

Department of Nephrology Dialysis and Transplantation, G Gaslini Children Institute, Genoa, Italy.

出版信息

Br J Clin Pract Suppl. 1996 Aug;85:18-20.

PMID:8995022
Abstract

Data on the effects of rhGH treatment in children on peritoneal dialysis are limited. In general rhGH therapy seems to be less effective compared with results on patients with chronic renal failure on conservative treatment. Our experience suggests that rhGH can stimulate growth in children on CPD, and that the efficacy of such therapy is reduced after the first year of treatment, although the rhGH is still active.

摘要

关于重组人生长激素(rhGH)治疗儿童腹膜透析效果的数据有限。总体而言,与慢性肾衰竭保守治疗患者的结果相比,rhGH治疗似乎效果较差。我们的经验表明,rhGH可刺激接受持续性非卧床腹膜透析(CPD)的儿童生长,并且尽管rhGH仍有活性,但治疗第一年之后这种疗法的疗效会降低。

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