血液透析患者对重组人生长激素（rhGH）的反应是否比慢性肾衰竭患者更无效？法国儿科肾脏病学会。
Is the response to rhGH in haemodialysis patients less effective than in patients with chronic renal failure? Société de Néphrologie Pédiatrique.
作者信息
Cochat P, Bérard E, André J L, Berlier P, Buttet C
机构信息
Unité de Néphrologie Pédiatrique, Hôpital Edouard Herriot, Lyon, France.
出版信息
Br J Clin Pract Suppl. 1996 Aug;85:21-2.
PMID:8995023
Abstract
A total of 82 prepubertal children with chronic renal insufficiency and with (HD, n = 28) or without (CRI, n = 54) haemodialysis were treated with rhGH, 1 i.u./kg/week. The absolute response (cm/year) was better in CRI children, but the growth velocity gain was similar in the two groups. In addition, the decrease in growth velocity during the second year on rhGH was more marked in CRI patients.
摘要
共有82名青春期前慢性肾功能不全儿童接受了重组人生长激素（rhGH）治疗，剂量为1国际单位/千克/周，其中28名进行血液透析（HD组），54名未进行血液透析（CRI组）。CRI组儿童的绝对反应（厘米/年）更好，但两组的生长速度增加相似。此外，CRI组患者在接受rhGH治疗的第二年生长速度下降更为明显。
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