Madsen O G
Acta Chir Scand. 1977;143(2):115-9.
From 1966 to 1972, 92 patients with bleeding duodenal ulcers were treated acutely by oversewing, selective gastric vagotomy and drainage. Seven patients (8%) died within the postoperative period. Subsequently 22 others have died, but from causes not associated with duodenum or stomach. One patient developed a pyloric cancer 4 years after the original operation. 53 patients could be follow-up with an observation time between 4 and 8 years. Six patients had undergone further surgery, three with duodenal ulcer recurrence six months, two years and four years, respectively, after the primary operation. One, after five years with an ulcer of the corpus of the stomach, and two others, eight months and four years, respectively, after primary operation, on suspicion of ulcer recurrence, which could not be confirmed. Three patients had severe dumping, and one, in incapacitating diarrhoea. 62% of the patients were graded in Visick group I, 19% in group II, 4% in group III and 15% in group IV. (Table III). No patient presented with recurrent bleeding, and no patient died from ulcer disease after discharge from hospital. The value of selective versus truncal vagotomy in treatment of bleeding duodenal ulcer is discussed, and it is concluded, that the procedure, which has to be performed, depends on the surgeon's experience in the vagotomy concerned.
1966年至1972年期间,92例十二指肠溃疡出血患者接受了缝合、选择性胃迷走神经切断术和引流等急性治疗。7例患者(8%)在术后期间死亡。随后又有22例患者死亡,但死因与十二指肠或胃无关。1例患者在初次手术后4年发生了幽门癌。53例患者得到随访,观察时间为4至8年。6例患者接受了进一步手术,其中3例分别在初次手术后6个月、2年和4年出现十二指肠溃疡复发。1例在初次手术后5年出现胃体溃疡,另外2例分别在初次手术后8个月和4年,因怀疑溃疡复发而接受手术,但未得到证实。3例患者出现严重倾倒综合征,1例出现严重腹泻。62%的患者属于Visick I组,19%属于II组,4%属于III组,15%属于IV组(表III)。没有患者出现复发性出血,也没有患者出院后死于溃疡病。文中讨论了选择性迷走神经切断术与全胃迷走神经切断术在治疗十二指肠溃疡出血方面的价值,并得出结论,具体实施哪种手术方法取决于外科医生在相关迷走神经切断术方面的经验。