Nitti V W, Kim Y, Combs A J
Department of Urology, New York University School of Medicine, Brooklyn, USA.
J Urol. 1997 Feb;157(2):600-3.
Persistent voiding dysfunction following transurethral resection of the prostate is not uncommon. We determined the correlation, if any, between the subjective complaints in men with voiding dysfunction after transurethral resection of the prostate and the urodynamic findings.
A total of 50 consecutive men with voiding dysfunction following transurethral resection of the prostate was evaluated with the American Urological Association symptom index and multichannel urodynamics. Patients with urethral stricture, urinary retention or prostate cancer were excluded from the study. Urodynamic parameters assessed included detrusor instability, bladder capacity, sphincteric insufficiency using the Valsalva leak point pressure, voiding pressure-flow studies as determined by the Abrams-Griffiths nomogram (obstructed, unobstructed or equivocal) and post-void residual.
Mean patient age was 71 years and mean interval from last transurethral resection of the prostate was 58 months (range 2 to 252). Mean total, obstructive and irritative symptom scores were 16.3, 5.8 and 10.5, respectively. A total of 20 patients (40%) complained of incontinence (14 urge and 6 stress). According to the Abrams-Griffiths nomogram 62% of the cases were unobstructed, 16% obstructed and 22% equivocal. Urodynamic abnormalities were demonstrated in 43 patients (86%), and included detrusor instability (54%), obstruction with or without detrusor instability (16%), sphincteric insufficiency (8%), detrusor hypocontractility (4%) and sensory urgency (4%). There was no difference in the total, irritative or obstructive scores among obstructed, unobstructed or equivocal cases. Similarly there was no difference in scores among patients with and without detrusor instability. Age, number of transurethral resections and interval since last transurethral resection were unrelated to pressure-flow results or detrusor instability. Post-void residual was significantly greater in obstructed cases and bladder capacity was significantly less in those with detrusor instability. The cause of incontinence was demonstrated in 19 of 20 patients (95%): 4 (20%) had sphincteric insufficiency and 15 (75%) had detrusor instability.
Symptoms are unreliable in predicting urodynamic findings with respect to obstruction and detrusor instability. There is a high incidence of detrusor instability in patients with voiding dysfunction after transurethral resection of the prostate. Urodynamic obstruction is a less likely occurrence.
经尿道前列腺切除术后持续性排尿功能障碍并不少见。我们确定了经尿道前列腺切除术后存在排尿功能障碍的男性患者的主观症状与尿动力学检查结果之间是否存在相关性(若有)。
对50例连续的经尿道前列腺切除术后存在排尿功能障碍的男性患者进行了美国泌尿外科学会症状指数评估和多通道尿动力学检查。尿道狭窄、尿潴留或前列腺癌患者被排除在研究之外。评估的尿动力学参数包括逼尿肌不稳定、膀胱容量、通过瓦尔萨尔瓦漏点压评估的括约肌功能不全、根据艾布拉姆斯-格里菲思列线图确定的排尿压力-流率研究(梗阻性、非梗阻性或不明确)以及残余尿量。
患者平均年龄为71岁,距上次经尿道前列腺切除术的平均间隔时间为58个月(范围为2至252个月)。平均总症状评分、梗阻性症状评分和刺激性症状评分分别为16.3、5.8和10.5。共有20例患者(40%)主诉尿失禁(14例急迫性尿失禁和6例压力性尿失禁)。根据艾布拉姆斯-格里菲思列线图,62%的病例为非梗阻性,16%为梗阻性,22%不明确。43例患者(86%)存在尿动力学异常,包括逼尿肌不稳定(54%)、伴或不伴逼尿肌不稳定的梗阻(16%)、括约肌功能不全(8%)、逼尿肌收缩力减弱(4%)和感觉性尿急(4%)。梗阻性、非梗阻性或不明确病例之间的总症状评分、刺激性症状评分或梗阻性症状评分无差异。同样,有或无逼尿肌不稳定的患者之间评分也无差异。年龄、经尿道前列腺切除术次数以及距上次经尿道前列腺切除术的间隔时间与压力-流率结果或逼尿肌不稳定无关。梗阻性病例的残余尿量显著更多,而逼尿肌不稳定患者的膀胱容量显著更小。20例患者中有19例(95%)尿失禁原因明确:4例(20%)存在括约肌功能不全,15例(75%)存在逼尿肌不稳定。
在预测梗阻和逼尿肌不稳定的尿动力学检查结果方面,症状并不可靠。经尿道前列腺切除术后存在排尿功能障碍的患者中,逼尿肌不稳定的发生率较高。尿动力学梗阻的情况较少见。