Carlson K V, Fiske J, Nitti V W
Department of Urology, New York University School of Medicine, New York, New York, USA.
J Urol. 2000 Nov;164(5):1614-8.
Lower urinary tract symptoms in women are often evaluated by cystometrography. We only assessed the bladder response to filling and not the impact of abnormal voiding, which is known to cause lower urinary tract symptoms. We determined the prevalence of voiding abnormalities in women with lower urinary tract symptoms and compared cystometrography to cystometrography plus voiding pressure flow study for evaluating this condition. We also determined whether storage or voiding symptoms predicted abnormal voiding.
We reviewed the records of 134 women who underwent video urodynamics with cystometrography and voiding pressure flow study to evaluate lower urinary tract symptoms. Patients with a history of neurological disease, grade 4 pelvic prolapse or a primary complaint of stress incontinence were excluded from study. All participants completed an American Urological Association symptom index and scores were subclassified as total, storage and voiding. A diagnosis was made in each case based on cystometrography findings, while any additional diagnoses when applicable were based on the voiding pressure flow study. Symptom scores were compared in women in whom the voiding study did and did not add information.
Mean patient age was 53.1 years (range 19 to 90). Voiding studies added information in 44 cases (33%), including dysfunctional voiding in 16, obstruction due to a moderate cystocele in 6, primary bladder neck obstruction in 6, external-detrusor sphincter dyssynergia as the initial presentation of neurological disease in 5, obstruction after incontinence surgery in 3, urethral stricture in 3, post-void contraction mimicking symptoms in 2, impaired contractility in 2 and an obstructing urethral diverticulum in 1. A total of 32 patients (24%) did not void during the study. Those with voiding abnormalities had higher total and voiding but similar storage symptom scores (23.1 versus 18.5, 12.3 versus 8.0 and 10.8 versus 10.5 points, p = 0.0008, 0.0001 and 0.58, respectively).
Women with lower urinary tract symptoms may have voiding abnormalities that are missed by cystometrography only. Voiding studies are useful for properly diagnosing and treating such cases. Women with abnormal voiding seem to have more severe voiding symptoms than those without such abnormalities. Occult neurological disease may also be identified in patients with lower urinary tract symptoms and voiding abnormalities.
女性下尿路症状常通过膀胱测压法进行评估。我们仅评估膀胱对充盈的反应,而非异常排尿的影响,已知异常排尿会导致下尿路症状。我们确定了下尿路症状女性中排尿异常的患病率,并比较了膀胱测压法与膀胱测压法加排尿压力流研究对该病症的评估情况。我们还确定了储尿或排尿症状是否可预测异常排尿。
我们回顾了134名接受视频尿动力学检查(包括膀胱测压法和排尿压力流研究)以评估下尿路症状的女性的记录。有神经疾病史、4级盆腔器官脱垂或主要主诉为压力性尿失禁的患者被排除在研究之外。所有参与者均完成了美国泌尿外科协会症状指数评估,分数被分为总分、储尿和排尿三类。每例病例根据膀胱测压结果进行诊断,适用时任何额外诊断基于排尿压力流研究。对排尿研究增加信息和未增加信息的女性的症状评分进行了比较。
患者平均年龄为53.1岁(范围19至90岁)。排尿研究在44例(33%)中增加了信息,包括功能性排尿障碍16例、中度膀胱膨出导致的梗阻6例、原发性膀胱颈梗阻6例、神经疾病初发表现为外括约肌-逼尿肌协同失调5例、尿失禁手术后梗阻3例、尿道狭窄3例、排尿后收缩模拟症状2例、收缩力受损2例以及梗阻性尿道憩室1例。共有32名患者(24%)在研究期间未排尿。有排尿异常的患者总分和排尿评分较高,但储尿症状评分相似(分别为23.1对18.5、12.3对8.0和10.8对10.5分,p分别为0.0008、0.0001和0.58)。
有下尿路症状的女性可能存在仅通过膀胱测压法会漏诊的排尿异常。排尿研究有助于正确诊断和治疗此类病例。有异常排尿的女性似乎比无此类异常的女性排尿症状更严重。在下尿路症状和排尿异常的患者中也可能发现隐匿性神经疾病。