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经皮腔内冠状动脉成形术与冠状动脉搭桥手术治疗多支冠状动脉疾病的长期疗效

Long-term outcome of percutaneous transluminal coronary angioplasty and coronary bypass surgery for multivessel coronary artery disease.

作者信息

Hara K, Suma H, Kozuma K, Horii T, Wanibuchi Y, Yamaguchi T, Tamura T

机构信息

Cardiovascular Center, Mitsui Memorial Hospital, Tokyo, Japan.

出版信息

Jpn Circ J. 1996 Dec;60(12):940-6. doi: 10.1253/jcj.60.940.

Abstract

We studied the short- and long-term outcomes of 97 patients treated with percutaneous transluminal coronary angioplasty (PTCA) and 72 patients treated with coronary artery bypass graft surgery (CABG) for multivessel coronary artery disease in a single hospital in 1989. Patients treated with CABG had a higher angina class, a higher incidence of diabetes mellitus and a greater extent of the disease. Complete revascularization was achieved in 61 patients (85%) with CABG and in 45 patients (46%) with PTCA (p < 0.001). Initial success of PTCA and CABG was obtained in 95% and 94% of the patients with PTCA and CABG, respectively. Actuarial survival rates at 5 years were similar (96% in the PTCA group; 94% in the CABG group). Fewer patients suffered from cardiac death or myocardial infarction in the CABG group than in the PTCA group, but this difference was not significant. The rate of survival free from death, myocardial infarction, CABG and repeat PTCA, was significantly higher in the CABG group than in the PTCA group (85% vs 48%; p < 0.001). These results suggest that CABG provides a favorable long-term outcome in patients with multivessel coronary artery disease and that PTCA provides a similar outcome in these patients when applied to suitable lesions, although more patients who undergo PTCA require repeat procedures.

摘要

1989年,我们在一家医院研究了97例接受经皮腔内冠状动脉成形术(PTCA)治疗的患者和72例接受冠状动脉旁路移植术(CABG)治疗的多支冠状动脉疾病患者的短期和长期预后。接受CABG治疗的患者心绞痛分级更高,糖尿病发病率更高,疾病范围更广。61例(85%)接受CABG治疗的患者和45例(46%)接受PTCA治疗的患者实现了完全血运重建(p<0.001)。PTCA和CABG的初始成功率分别在接受PTCA和CABG治疗的患者中为95%和94%。5年的精算生存率相似(PTCA组为96%;CABG组为94%)。CABG组中心脏死亡或心肌梗死的患者比PTCA组少,但这种差异不显著。CABG组中无死亡、心肌梗死、CABG和重复PTCA的生存率显著高于PTCA组(85%对48%;p<0.001)。这些结果表明,CABG为多支冠状动脉疾病患者提供了良好的长期预后,而PTCA应用于合适病变时在这些患者中提供了相似的预后,尽管更多接受PTCA的患者需要重复手术。

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