Bouvard M, Mollard E, Guerin J, Cottraux J
Anxiety Treatment Unit, Hôpital, Neurologique, Lyon, France.
Psychother Psychosom. 1997;66(1):27-32. doi: 10.1159/000289102.
The change of psychopathological dimensions during treatment of panic disorder is attracting increasing interest.
A population of subjects experiencing panic disorder with agoraphobia is evaluated with the French version of the factor structure of the Symptom Checklist 90 R (SCL 90 R). Two groups of patients are compared: a group receiving cognitive behaviour therapy (CBT) combined with buspirone and a group receiving cognitive behaviour therapy combined with placebo.
Comparative analysis of pre- and post-test changes between both groups completing treatment showed that the combination cognitive behaviour therapy plus buspirone provided better results than those in patients who had received cognitive behaviour therapy plus placebo. This difference between treatments did not persist at the 1-year follow-up, since, while results had been effectively maintained in the CBT plus buspirone group, the CBT plus placebo group continued to improve significantly for the target dimensions of treatment.
Psychopathological dimensions on the SCL 90 R show that combination of buspirone and cognitive behaviour therapy accelerates the behaviour modification process only in the short term.
惊恐障碍治疗期间心理病理维度的变化正吸引着越来越多的关注。
采用症状自评量表90修订版（SCL 90 R）因子结构的法语版本对一群患有广场恐怖症的惊恐障碍患者进行评估。比较两组患者：一组接受认知行为疗法（CBT）联合丁螺环酮治疗，另一组接受认知行为疗法联合安慰剂治疗。
对两组完成治疗后的前后测试变化进行比较分析，结果显示认知行为疗法联合丁螺环酮治疗组比接受认知行为疗法联合安慰剂治疗的患者效果更好。治疗之间的这种差异在1年随访时未持续存在，因为虽然CBT联合丁螺环酮组的疗效得到了有效维持，但CBT联合安慰剂组在治疗的目标维度上继续显著改善。
SCL 90 R上的心理病理维度表明，丁螺环酮与认知行为疗法的联合仅在短期内加速行为改变过程。
