Christiansen T N, Freije J E, Neuburg M, Roza A
Department of Otolaryngology and Human Communication, MCW Clinic, Froedtert Hospital, Milwaukee, Wisconsin 53226, USA.
Clin Transplant. 1996 Dec;10(6 Pt 1):561-3.
Parotid metastases from cutaneous neoplasms are rare and have a relatively good prognosis if limited to the lymph nodes. When extension beyond the lymph nodes occurs, prognosis is grave. It has also been reported that transplant patients have a higher incidence of cutaneous carcinoma, which tends to be more aggressive. We report a case of an aggressive squamous cell carcinoma metastatic to the parotid gland in a liver transplant patient. The literature pertaining to parotid area metastasis and cancer in transplant recipients is reviewed. We conclude that clinicians should have a higher clinical index of suspicion for cutaneous lesions in transplant patients and that cutaneous lesions at risk for metastasis to the parotid should be treated more aggressively.
皮肤肿瘤的腮腺转移瘤较为罕见，若仅局限于淋巴结，其预后相对较好。当肿瘤超出淋巴结范围时，预后则较差。也有报道称，移植患者皮肤癌的发病率较高，且往往更具侵袭性。我们报告了一例肝移植患者发生侵袭性鳞状细胞癌转移至腮腺的病例。并对有关移植受者腮腺区域转移和癌症的文献进行了综述。我们得出结论，临床医生应对移植患者的皮肤病变保持更高的临床怀疑指数，对于有转移至腮腺风险的皮肤病变应采取更积极的治疗措施。
