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小剂量阿糖胞苷治疗急性非淋巴细胞白血病

Low dose cytosine arabinoside in the treatment of acute non-lymphoblastic leukemia.

作者信息

Insiripong S, Thaisamakr S

机构信息

Department of Medicine, Maharat Nakhon Ratchasima Hospital, Thailand.

出版信息

J Med Assoc Thai. 1996 Sep;79(9):568-71.

PMID:8996985
Abstract

Low-dose ARA-C (10 mg/m2 subcutaneous injection twice/day for 20 days with 10 days rest) was prescribed in 8 cases of newly diagnosed ANLL. Only one case attained complete remission in 2 courses and lasted for one and a half years without maintenance therapy. She was 63 years of age. The drug could be tolerated well and no serious side effect was observed.

摘要

对8例新诊断的急性非淋巴细胞白血病患者采用小剂量阿糖胞苷(10mg/m²皮下注射,每日2次,共20天,休息10天)治疗。仅1例在2个疗程后达到完全缓解,且未进行维持治疗,缓解持续了一年半。该患者63岁。药物耐受性良好,未观察到严重副作用。

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