Maleemonkol S, Chareonium V, Isariyodom P, Faichamnan S
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
J Med Assoc Thai. 1996 Oct;79(10):648-53.
From January 1984 to December 1994, 36 women with granulosa cell tumors of the ovary were treated at Maharaj Nakorn Chiang Mai Hospital, which accounted for 5.8 per cent of all 620 ovarian malignancies treated at this institute. Twenty patients were in stage I, 2 in stage II, 11 in stage III and the remaining 3 cases were in stage IV. Most patients had unilateral ovarian involvement while 6 (16.7%) had bilateral involvement. The diameter of the tumor ranged from 4 to 30 cm with the median of 14 cm. Treatment consisted of hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy in most cases. To date 10 patients have no evidence of disease while 9 died of the disease, others were lost to follow-up. The 5-year survival was 94 per cent in the early stages compared to 25 per cent in advanced stages. The overall survival rate was 62.7 per cent for all stages.
1984年1月至1994年12月期间,清迈玛哈叻吉医院收治了36例卵巢颗粒细胞瘤患者,占该机构收治的620例卵巢恶性肿瘤患者的5.8%。20例患者为Ⅰ期,2例为Ⅱ期,11例为Ⅲ期,其余3例为Ⅳ期。大多数患者单侧卵巢受累,6例(16.7%)双侧受累。肿瘤直径为4至30厘米,中位数为14厘米。治疗方法包括子宫切除术和双侧输卵管卵巢切除术,大多数病例随后进行化疗。迄今为止,10例患者无疾病证据,9例死于该病,其他患者失访。早期5年生存率为94%,晚期为25%。所有阶段的总生存率为62.7%。