Matsumoto K, Takahashi Y, Yoshitake S, Noguchi T
Department of Anesthesiology, Oita Medical University.
Masui. 1996 Dec;45(12):1525-8.
Perioperative hemorrhage in patients undergoing surgery is a major cause of morbidity and mortality. DRIHEMATO SYSTEM COAG-1 can detect prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) easily. We combined this monitor with platelet count (PLT), activated clotting time (ACT) and thromboelastography (TEG) and devised a hematologic monitoring system for bedside use. This study of 10 adults undergoing cardiopulmonary bypass was conducted to determine the utility of this monitoring system. The specificity for lotting abnormality of this monitoring system included the following values; PT = 88%, FIB = 100% and TEG = 67%. This study suggests that this monitoring system may be useful in early diagnosis and treatment of postoperative coagulopathy.
接受手术的患者围手术期出血是发病和死亡的主要原因。DRIHEMATO SYSTEM COAG-1能够轻松检测凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)和纤维蛋白原(FIB)。我们将该监测仪与血小板计数(PLT)、活化凝血时间(ACT)和血栓弹力图(TEG)相结合,设计了一种用于床边的血液学监测系统。本研究对10名接受体外循环的成年人进行,以确定该监测系统的效用。该监测系统对凝血异常的特异性包括以下数值:PT = 88%,FIB = 100%,TEG = 67%。本研究表明,该监测系统可能有助于术后凝血病的早期诊断和治疗。