Tamaki Y, Fukuda M, Kishida T
Department of Forensic Medicine, Oita Medical University, Japan.
Nihon Hoigaku Zasshi. 1996 Dec;50(6):427-9.
In this deficiency duo case, the plasma that had been left over after clinical diagnostic tests was the only blood sample available from the deceased alleged mother. Since her blood had been ABO grouped during hospitalization, we tested the plaintiff for the ABO system first. Then, to draw as much genetic information as possible from their plasma, we phenotyped 13 plasma protein systems and, three and a half years later, analyzed three short tandem repeat (STR) loci. The conventional phenotyping and STR genotyping gave probabilities of maternity of 0.974 and 0.967, respectively, bringing the total probability to 0.999. The present study highlights the utility of plasma STR typing in case of need.
在这个双缺陷案例中，临床诊断测试后剩余的血浆是唯一可从已故所谓母亲处获得的血样。由于她住院期间已进行ABO血型分组，我们首先对原告进行了ABO系统检测。然后，为了从他们的血浆中获取尽可能多的遗传信息，我们对13个血浆蛋白系统进行了表型分析，并在三年半后分析了三个短串联重复（STR）基因座。传统的表型分析和STR基因分型得出的亲权概率分别为0.974和0.967，总概率达到0.999。本研究强调了在有需要的情况下血浆STR分型的实用性。
