Popli A P, Hegarty J D, Siegel A J, Kando J C, Tohen M
Consolidated Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Psychosomatics. 1997 Jan-Feb;38(1):35-7. doi: 10.1016/s0033-3182(97)71501-9.
The authors review their experience with transfers of hospitalized psychiatric inpatients to general hospitals because of adverse drug reactions (ADRs). A total of 29 medical transfers related to ADRs were found in a review of 10,994 psychiatric inpatient admissions that occurred in a 30-month period between 1990 and 1993 (0.264%). Most cases involved neurological syndromes (76%), particularly delirium (31%). Low-potency antipsychotic agents were most frequently implicated (31%). Most ADRs were of moderate severity, but 8 cases required medical hospitalization (0.07% incidence). These findings indicate that ADRs leading to transfer of hospitalized psychiatric patients to a general medical facility were infrequent (< 0.3% of psychiatric admissions) and rarely led to medical hospitalization (< 0.1%).
作者回顾了因药物不良反应（ADR）而将住院精神科患者转至综合医院的经历。在对1990年至1993年30个月期间发生的10994例精神科住院患者入院情况的回顾中，共发现29例与ADR相关的医疗转院（0.264%）。大多数病例涉及神经综合征（76%），尤其是谵妄（31%）。低效价抗精神病药物最常被牵连（31%）。大多数ADR为中度严重程度，但有8例需要住院治疗（发病率0.07%）。这些发现表明，导致住院精神科患者转至综合医疗机构的ADR并不常见（<精神科入院患者的0.3%），且很少导致住院治疗（<0.1%）。
