Konrádová V, Uhlík J, Vajner L, Zajícová A, Zocová J
Institute of Histology and Embryology, 2nd Medical Faculty, Charles University, Prague, Czech Republic.
Folia Biol (Praha). 1996;42(5):261-6.
The ultrastructure of the tracheal epithelium was studied 5 and 20 min after intravenous (i.v.) administration of 0.5 mg of acetylcholine. As a result of this treatment, the goblet cells were overstimulated and damaged, and the mechanism of their secretion was accelerated. Only a mild pathological alteration was encountered in the ciliated cells. According to our classification, the degree of secretory element damage was severe, the injury to the ciliary border was moderate. The morphological signs of the severe impairment of the self-cleaning ability of the epithelium were inspissated mucus and very numerous bacteria in the area among free cilia.
在静脉注射0.5毫克乙酰胆碱后5分钟和20分钟，对气管上皮的超微结构进行了研究。这种处理的结果是，杯状细胞受到过度刺激并受损，其分泌机制加快。纤毛细胞仅出现轻度病理改变。根据我们的分类，分泌成分损伤程度严重，纤毛边界损伤为中度。上皮自我清洁能力严重受损的形态学迹象是游离纤毛区域内黏液浓缩和大量细菌。
