Drabo P Y, Kabore J, Lengani A
Service de Médecine interne, Ouagadougou 01.
Bull Soc Pathol Exot. 1996;89(3):191-5.
It is a four year study (1991 January to 1994 December) on four hundred diabetic people in Ouagadougou, aiming to assess the complications observed in these patients. The search of these complications have been systematic during the first consultation and during the follow-up through clinical examination and complementary exams. Most of classic complications have been found and can be split in two groups: 1) acute complications which included: metabolic ones observed on 17.5% of the patients (ketoacidosis 5%, hypoglycemia 11.2% and hyperosmolar coma 1.2%); infectious complications observed on 79% of the patients. The high frequency of these complications testifies of the difficulties of the management, under-information and insufficient education of the patients; 2) degenerative chronic complications including: microangiopathy: retinopathy (15.8%) and nephropathy (24.8%) which was complicated by chronic uremia in 9% cases; macroangiopathy in which: gangrene (7.5%), hypertension (20%), cardiac disease (8.7%), neurologic complications (35%) were the most frequent. These chronic complications accentuate mortality and morbidity linked to diabetes and increase the economical and social cost of this affection in a poor environment.
这是一项为期四年（1991年1月至1994年12月）的针对瓦加杜古400名糖尿病患者的研究，旨在评估这些患者中观察到的并发症。在首次就诊期间以及随访过程中，通过临床检查和辅助检查对这些并发症进行了系统的排查。发现了大多数经典并发症，可分为两组：1）急性并发症，包括：17.5%的患者出现代谢性并发症（酮症酸中毒5%，低血糖11.2%，高渗性昏迷1.2%）；79%的患者出现感染性并发症。这些并发症的高发生率证明了管理的困难、患者信息不足和教育不够；2）退行性慢性并发症，包括：微血管病变：视网膜病变（15.8%）和肾病（24.8%），其中9%的病例并发慢性尿毒症；大血管病变，其中：坏疽（7.5%）、高血压（20%）、心脏病（8.7%）、神经并发症（35%）最为常见。这些慢性并发症加剧了与糖尿病相关的死亡率和发病率，并增加了在贫困环境中这种疾病的经济和社会成本。
