Rey J L, Cavallo J D, Milleliri J M, L'Hoest S, Soares J L, Piny N, Coue J C, Jouan A
Service de biologie médicale, Hôpital des armées Bégin, Saint-Mandé.
Bull Soc Pathol Exot. 1996;89(3):204-8.
After the outbreaks of cholera, dysenteriae, meningitidis of which the rwandese refugees have been the victims in August and September 1994 in the camps of the Goma's area (Zaïre), the medical teams were confronted with a great number of fevers of unknown origin. In order to explore the possible etiologies, we have conducted a cases/controls study (n = 96). Clinically, the cases occur more frequently than controls headache (p < 0.001), splenomegaly (p = 0.02) and neutropeny (p < 0.001) Serologically, it has been constated non significantly difference between cases and controls, but prevalence of HIV-1 infections (19 and 6%) and arbovirus (23 and 10%) infections are very high. Arbovirosis could explain, partially or associated with HIV and tuberculosis, the presence of these fevers undeterminated more than malaria or typhus epidemic.
1994年8月和9月，卢旺达难民在扎伊尔戈马地区的营地中成为霍乱、痢疾、脑膜炎疫情的受害者，之后，医疗队面临大量不明原因发热病例。为探究可能的病因，我们开展了一项病例对照研究（n = 96）。临床上，病例组出现头痛（p < 0.001）、脾肿大（p = 0.02）和中性粒细胞减少（p < 0.001）的频率高于对照组。血清学方面，病例组与对照组之间未发现显著差异，但HIV-1感染率（19%和6%）和虫媒病毒感染率（23%和10%）非常高。虫媒病毒感染可能部分解释这些不明原因发热，或与HIV和结核病共同导致这些发热，而非疟疾或斑疹伤寒流行。
