Rev Epidemiol Sante Publique. 1996 Aug;44(4):358-63.
In 1994, between July 14 and July 20, around one million of Rwandan refugees fled to the North Kivu region of Zaire. In spite of the existence of favorable conditions for cholera, it was necessary to wait until the laboratories isolated the first strain of cholera, on July 20 and 21, before the international community took action in one of the most important outbreaks of cholera known. The total number of cases of cholera was 36 471, of which half occurred between July 21 and July 27, reaching a peak on July 26. The average overall mortality was 28 per 10,000 in the second half of July, and 5 per 10,000 in the first half of August. 85 percent of the deaths are associated with diarrhea and 60 percent of these deaths with diarrhea are caused by cholera, the other being caused by dysentery. From July 24 to September 17, the Bioforce laboratory (French army) carried out 396 coprocultures : it isolated 78 strains of cholera (Vibrio cholerae 01, biotype El Tor, serotype Ogawa, resisting at O129, without indole), and 77 strains of shigella (Shigella dysenteriae type 1). There were several causes of this outbreak, among which the most important was the lack of water : during the first week, the average available of water was been evaluated at 200 ml per day per person ; the other causes of this outbreak were the impossibility to dig latrines, the lack of hygiene, the level of health and the promiscuity among the refugees. One of the modalities to limit this outbreak of cholera would probably have been to anticipate the subsequent cases and deaths by a massive international response adapted to this risk, as soon the Rwandan refugees began to flood in Goma.
1994年7月14日至7月20日期间,约100万卢旺达难民逃往扎伊尔的北基伍地区。尽管存在霍乱流行的有利条件,但必须等到实验室于7月20日和21日分离出第一株霍乱菌株后,国际社会才在已知最重要的霍乱疫情之一中采取行动。霍乱病例总数为36471例,其中一半发生在7月21日至7月27日之间,7月26日达到峰值。7月下半月的总体平均死亡率为每万人28例,8月上半月为每万人5例。85%的死亡与腹泻有关,其中60%的腹泻死亡由霍乱引起,其他由痢疾引起。7月24日至9月17日,生物力量实验室(法国军队)进行了396次粪便培养:分离出78株霍乱菌株(霍乱弧菌O1型,埃尔托生物型,小川血清型,对O129耐药,无吲哚)和77株志贺氏菌(痢疾志贺氏菌1型)。此次疫情有多种原因,其中最重要的是缺水:在第一周,人均每日可用水量估计为200毫升;此次疫情的其他原因包括无法挖掘厕所、缺乏卫生条件、健康水平以及难民之间的混居情况。限制此次霍乱疫情爆发的一种方式可能是,一旦卢旺达难民开始涌入戈马,就通过大规模的国际应对措施来预测后续的病例和死亡情况,以应对这种风险。