Okuyama E, Okamoto Y, Yamazaki M, Satake M
Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Chem Pharm Bull (Tokyo). 1996 Feb;44(2):333-6. doi: 10.1248/cpb.44.333.
From Jatropha cilliata M. Arg., a Peruvian medicinal plant, isoorientin and orientin were isolated as anxiolytic components by using the isolation guide of anti-conflict effect in mice. Several related flavonoids were also tested for this effect. Another bioassay-guided isolation using the acetic acid-induced writhing method gave a coumarin compound, fraxetin, as an analgesic principle.
从秘鲁药用植物蓖麻叶麻疯树中,通过利用小鼠抗冲突效应的分离指南,异荭草苷和荭草苷被分离为抗焦虑成分。还对几种相关黄酮类化合物进行了该效应测试。另一种使用乙酸诱导扭体法的生物测定导向分离得到了一种香豆素化合物七叶亭,作为镇痛成分。