[硒化合物在红细胞冷冻保存中的保护作用]
[Protective effect of selenium compounds in the freeze preservation of erythrocytes].
作者信息
Matthes G, Hackensellner H A, Jentzsch K D, Krause W, Oehme P
出版信息
Folia Haematol Int Mag Klin Morphol Blutforsch. 1979;106(3):394-8.
PMID:89991
Abstract
The influence of sodium selenite, selenomethionine and sodium selenite with tocopherols in combination on the survival of cryopreserved erythrocytes was investigated. Percent hemolysis is marked decreased after a three-hour incubation of the whole blood with addition of selenomethionine as well as sodium selenite with tocopherole in combination before cryopreservation. The protective effect is attributed to the antioxydative and membrane stabilizing effectiveness of selenium and tocopherol.
摘要
研究了亚硒酸钠、硒代蛋氨酸以及亚硒酸钠与生育酚联合使用对冷冻保存红细胞存活率的影响。在冷冻保存前，将全血与硒代蛋氨酸以及亚硒酸钠与生育酚联合添加物一起孵育三小时后，溶血百分比显著降低。这种保护作用归因于硒和生育酚的抗氧化及膜稳定作用。
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