Ferrer J, Balcells E, Orriols R, Villarino M A, Drobnic Z, Morell F
Servicio de Neumología, Hospital General Universitario Vall d'Hebron, Barcelona.
Med Clin (Barc). 1996 Oct 26;107(14):535-8.
Up to now, only 2 cases of benign asbestos pleural effusion have been described in Spain. We report our experience of 15 patients diagnosed of benign asbestos pleural effusion (BAPE). Between 1980 and January 1995, 15 patients were diagnosed of BAPE according to the following criteria: a) evidence of pleural effusion; b) previous asbestos exposure, and c) exclusion of other etiologies of last during 3 years of follow-up. Retrospective review of diagnostic and evolutive data from the patients' clinical records. Asbestos exposure was intense in 8 patients and slight in 7. There were 11 effusions on the left side and 4 on the right side. All effusions were exudative, with a pleural adenosine deaminase level lower than 43 U/l. Eleven patients had a lymphocytic pleural fluid. All patients had nonspecific pleural histology, and asbestos bodies were detected in one case. Eleven patients achieved a radiographic resolution in less than 3 months, and 3 patients presented relapses. Fourteen patients had a good outcome, and one patient presented a lung adenocarcinoma after 5 years of follow-up. Benign asbestos pleural effusions are predominant on the left side, have a tendency to relapse and the exposition can be occasional. The outcome is good in most of the cases.
截至目前,西班牙仅报道过2例良性石棉性胸腔积液病例。我们报告了15例被诊断为良性石棉性胸腔积液(BAPE)患者的情况。在1980年至1995年1月期间,15例患者根据以下标准被诊断为BAPE:a)有胸腔积液的证据;b)既往有石棉接触史;c)在3年随访期间排除其他病因。对患者临床记录中的诊断和病情发展数据进行回顾性分析。8例患者石棉接触情况严重,7例轻微。左侧有11例胸腔积液,右侧有4例。所有胸腔积液均为渗出性,胸腔腺苷脱氨酶水平低于43 U/l。11例患者胸腔积液为淋巴细胞性。所有患者胸膜组织学均无特异性,仅1例检测到石棉小体。11例患者在不到3个月内影像学表现消退,3例复发。14例患者预后良好,1例患者在随访5年后发生肺腺癌。良性石棉性胸腔积液以左侧为主,有复发倾向,接触石棉情况可能为偶发。大多数病例预后良好。