Simon K
katedry i Kliniki Chorób zakaźnych Ak. Med. we Wrocławiu.
Wiad Lek. 1994 Nov-Dec;47(21-24):854-8.
In the paper the structure, place od synthesis and biological role of fibronectin in human organism are discussed, and the value of plasma fibronectin (FN) concentration determination in the diagnosis of chronic hepatic diseases, including hepatic fibrosis, was critically evaluated. Simultaneously, the view is presented that the determination of FN concentration in peritoneal fluid, as well the determination of amount and location of FN in the hepatic tissue should be a routine element of hepatological diagnosis.
本文讨论了纤连蛋白在人体中的结构、合成部位及生物学作用,并对血浆纤连蛋白(FN)浓度测定在包括肝纤维化在内的慢性肝病诊断中的价值进行了批判性评估。同时,提出腹腔液中FN浓度的测定以及肝组织中FN的含量和定位测定应成为肝病诊断的常规项目。