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[精神分裂症样障碍患者的前瞻性研究:一种疾病分类学困境?]

[A prospective study of patient with schizophreniform disorder: a nosological dilemma?].

作者信息

Chinchilla Moreno A, Vega Piñero M, Cebollada Gracia A, Montes Rodríguez J M, Díaz Marsa M

机构信息

Servicio de Psiquiatría, Hospital Ramón Cajal, Madrid.

出版信息

Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1996 Sep-Oct;24(5):245-51.

PMID:8999723
Abstract

We study retrospectively 42 inpatients of the psychiatry department of the Ramón y Cajal Hospital, through a period between 1st January of 1988 and the 31st December 1993. All of them were diagnosed at discharge of schizophreniform disorder according to DSM-III R diagnostic criteria and it was in all of them the index episode of the psychosis. Sociodemographic, clinical, evolutive, and therapeutical variables are analyzed. We made a new assessment of the patients in the sample during April 1994 through a direct interview. The mean follow-up period was 4.18 years. The main results were: A predominance of male/female proportion (2/1), nearly half of the sample had emotional or psychosocial stressors previous to the episode. Previous schizoid personality traits were found in 57.1%. 11.9% had first degree relatives antecedents of schizophrenia and 19% of non-bipolar affective disorders. At follow-up 40.4% needed to be hospitalized again. It is noteworthy that 80.9% were rediagnosed during follow-up as schizophrenia.

摘要

我们回顾性研究了拉蒙·伊·卡哈尔医院精神科的42名住院患者,研究时间段为1988年1月1日至1993年12月31日。所有患者出院时均根据《精神疾病诊断与统计手册》第三版修订版(DSM-III R)诊断标准被诊断为精神分裂症样障碍,且均处于精神病的首次发作期。对社会人口统计学、临床、病情演变及治疗变量进行了分析。1994年4月,我们通过直接访谈对样本中的患者进行了重新评估。平均随访期为4.18年。主要结果如下:男女比例为2/1,近一半的样本在发病前有情感或心理社会应激源。57.1%的患者有先前的分裂样人格特质。11.9%的患者有精神分裂症的一级亲属病史,19%的患者有非双相情感障碍病史。随访时,40.4%的患者需要再次住院。值得注意的是,80.9%的患者在随访期间被重新诊断为精神分裂症。

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