Rivet B, Bougerol T, Cura B, Llorca P M, Lançon C, Scotto J C
Service Hospitalo-Universitaire de Psychiatrie d'Adultes, Hôpital Sainte-Marguerite, Marseille.
Encephale. 1994 Jan-Feb;20(1):17-25.
The computerized medical file, used in routine work in an Adult Psychiatry University-Hospital Unit enabled us to select 113 cases among 1,000 consecutive hospitalizations, the diagnosis of which could possibly lead to schizophrenia. These cases which we named "paraschizophrenic states" are linked to DSM III-R criteria of borderline (27 cases), schizoid (40 cases) or schizotypical (15 cases) personalities, schizophreniform trouble and unspecified psychotic trouble (17 cases), brief reactional psychosis (14 cases). We selected 196 cases of schizophrenia in the same cohort of hospitalized patients. As it is now usually admitted, we marked out two subgroups in this second group: the positive schizophrenia which gather together the paranoid and undifferentiated patterns and the negative schizophrenia which correspond to disorganized, catatonic and residual models, according to DSM III-R criterion. We compared the "paraschizophrenic states'" group and its five subgroups (we indeed joined schizophreniform trouble and unspecified psychotic trouble under the name of "other psychotic trouble" by reason of their relative nosographic lacks of precision and of their too small sizes) with the schizophrenia's group and its two subgroups. Each group is matched for sex (1.51 men for 1 woman in the first group and 1.45 men for 1 woman in the second group). We evaluated statistics for markers usually studied in schizophrenia in each subgroup. These markers are of three classes: biographical: age during the study, age of troubles' onset, season of birth; socioeconomic: socioeconomic level of family and patient's student status; psychiatric: family (history affective trouble, psychotic trouble, alcoholism), treatment response and short- and middle-term prognosis.(ABSTRACT TRUNCATED AT 250 WORDS)
在一所大学附属医院成人精神病科日常工作中使用的计算机化医疗档案,使我们能够在连续1000例住院病例中挑选出113例,这些病例的诊断可能会导致精神分裂症。我们将这些病例命名为“类精神分裂症状态”,它们与DSM III - R标准中的边缘型(27例)、分裂样(40例)或分裂型(15例)人格障碍、精神分裂症样障碍和未特定的精神病性障碍(17例)、短暂反应性精神病(14例)相关。我们在同一住院患者队列中挑选出196例精神分裂症病例。正如现在通常所认可的,我们在第二组中划分出两个亚组:根据DSM III - R标准,阳性精神分裂症包括偏执型和未分化型模式,阴性精神分裂症对应紊乱型、紧张型和残留型模式。我们将“类精神分裂症状态”组及其五个亚组(由于“精神分裂症样障碍”和“未特定的精神病性障碍”在疾病分类学上相对缺乏精确性且病例数过少,我们将它们合并为“其他精神病性障碍”)与精神分裂症组及其两个亚组进行比较。每组在性别上进行了匹配(第一组男性与女性比例为1.51∶1,第二组为1.45∶1)。我们评估了每个亚组中通常在精神分裂症研究中所涉及的标志物的统计数据。这些标志物分为三类:个人经历类:研究期间的年龄、发病年龄、出生季节;社会经济类:家庭社会经济水平和患者的学生身份;精神科类:家族史(情感障碍、精神病性障碍、酗酒)、治疗反应以及短期和中期预后。(摘要截选至250词)