Fayemi A O, Deppisch L M
Am J Clin Pathol. 1977 Sep;68(3):393-6. doi: 10.1093/ajcp/68.3.393.
Six cases of coronary embolism and myocardial infarction associated with nonbacterial thrombotic endocarditis were seen at the Mount Sinai Hospital over a ten-year period. Every patient had an underlying malignant neoplasm. The vegetations were found on aortic, mitral, tricuspid and pulmonic valves and were located on the free or closure margins. The clinical diagnosis of this condition is difficult because of simultaneous embolization to the brain, causing widespread neurologic symptoms, but could be made by electrocardiographic and serum enzyme studies. Myocardial infarction caused the deaths of three patients. The relationship between nonbacterial thrombotic endocarditis, hypercoagulability, and disseminated intravascular coagulation is discussed.
在十年期间，西奈山医院共收治了6例与非细菌性血栓性心内膜炎相关的冠状动脉栓塞和心肌梗死患者。每位患者均患有潜在的恶性肿瘤。赘生物见于主动脉瓣、二尖瓣、三尖瓣和肺动脉瓣，位于游离缘或闭合缘。由于同时发生脑栓塞，导致广泛的神经症状，这种疾病的临床诊断很困难，但可通过心电图和血清酶学检查做出诊断。心肌梗死导致3例患者死亡。文中讨论了非细菌性血栓性心内膜炎、高凝状态和弥散性血管内凝血之间的关系。
