Pratt-Thomas H R, Smith R M, McMaster K R, Earlywine G R
Pathol Res Pract. 1980 Dec;170(4):328-37. doi: 10.1016/S0344-0338(80)80038-0.
Three cases of adenocarcinoma that were complicated by nonbacterial thrombotic endocarditis and disseminated intravascular coagulation are described. In two of these cases mucin was demonstrable within vascular channels as well as within the thrombotic vegetations of the cardiac valves. This intravascular mucin was also responsible for vascular occlusion with resultant infarction in such organs as heart and brain. Intravascular mucin of this magnitude has not been previously recorded and mucinous accumulations behaving as thromboemboli with infarcts have not been heretofore described.
本文描述了3例腺癌合并非细菌性血栓性心内膜炎和弥散性血管内凝血的病例。其中2例,在血管腔以及心脏瓣膜血栓性赘生物内均可检测到黏液。这种血管内黏液还导致血管闭塞,进而造成心脏和脑等器官梗死。如此大量的血管内黏液此前未见报道,黏液性积聚表现为血栓栓子并伴有梗死的情况也未曾有过描述。