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肝硬化与妊娠。一例病例报告及文献综述。

Cirrhosis and pregnancy. A case report and review of the literature.

作者信息

Restaino A, Campobasso C, D'Aloya A, Abbruzzese A D, Valerio A, Pansini F

机构信息

Dpt, of Obstetrics and Gynecology, University of Bari, Italy.

出版信息

Clin Exp Obstet Gynecol. 1996;23(4):240-7.

PMID:9001787
Abstract

A clinical case of a pregnant suffering from hepatic cirrhosis with ascites, splenomegaly and portal hypertension is described. The pregnancy carried on till the 31st week, even though with the repeated use of tocholytic agents. Cesarean section was performed because of the onset of serious jaundice and the decline of general maternal conditions. The infant, who had an Apgar score of 8 at the 1st and 5th minute, died on the 10th day because of accuse haemorrhagic interstitial pneumonitis in premature lungs and hepatopathy associated with widespread jaundice. The mother was discharged on the 25th day of the postpartum period, in light of the net improvement of her general metabolic condition, the sudden regression of the jaundice and the decrease of the cholestasis indices. A review of the literature discussing maternal complications fetal risks, management of pregnancy and delivery and outcome of the newborn are presented.

摘要

本文描述了一例患有肝硬化并伴有腹水、脾肿大和门静脉高压的孕妇临床病例。尽管反复使用了宫缩抑制剂,妊娠仍持续至31周。由于出现严重黄疸和产妇一般状况恶化,进行了剖宫产。该婴儿出生时1分钟和5分钟Apgar评分均为8分,但在第10天因早产肺出血性间质性肺炎和伴有广泛黄疸的肝病而死亡。鉴于产妇一般代谢状况明显改善、黄疸突然消退以及胆汁淤积指标下降,母亲在产后第25天出院。本文还对讨论孕产妇并发症、胎儿风险、妊娠和分娩管理以及新生儿结局的文献进行了综述。

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1
Cirrhosis and pregnancy. A case report and review of the literature.肝硬化与妊娠。一例病例报告及文献综述。
Clin Exp Obstet Gynecol. 1996;23(4):240-7.
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Pregnancy in a patient with portal hypertension secondary to liver cirrhosis.肝硬化继发门静脉高压患者的妊娠情况。
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Cirrhosis and portal hypertension in pregnancy.妊娠期肝硬化与门静脉高压
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引用本文的文献

1
Pregnancy in women with liver cirrhosis is associated with increased risk for complications: A systematic review and meta-analysis of the literature.妊娠合并肝硬化女性相关并发症风险增加:系统评价和文献荟萃分析。
BJOG. 2022 Sep;129(10):1644-1652. doi: 10.1111/1471-0528.17156. Epub 2022 Mar 31.