Sawaguchi H, Ogawa T, Takano T, Sato K
Department of Pediatrics, Oita Medical University, School of Medicine, Japan.
Acta Paediatr Jpn. 1996 Dec;38(6):580-9. doi: 10.1111/j.1442-200x.1996.tb03712.x.
The purpose of the present study was to clarify the developmental changes of electroencephalogram (EEG) background activity in term and preterm infants that take place with increasing conceptional age (CA) through an autoregressive (AR) model. Polygraphical EEG recordings were obtained from 76 healthy term and preterm infants with a CA ranging between 31 and 40 weeks. Decreases in total power and component power of delta were noted with CA during burst activity (BA) in quiet sleep (QS) and during active sleep (AS). Increases in total power and component power of delta were noted with CA during interburst interval activity (IBIA) of QS. Regression analysis (RA) of the information amount (IA) indicated a negative correlation with increasing CA in AS and in the monopolar EEG tracings Fp1, C3, O1 and O2 in BA, and a positive correlation in O1 in IBIA. Regression analysis of the IA of delta indicated a negative correlation with increasing CA in AS and in Fp1, C3, O1 and O2 in BA, and a positive correlation in O1 in IBIA. Regression analysis of the IA of delta indicated a negative correlation with increasing CA in BA and AS. These results showed that the high voltage slow wave component changed to a low voltage slow one with development in AS and that BA was longer in duration and lower in power with increasing CA, while IBIA was shorter in duration and higher in power. In conclusion, significant developmental changes occur in all derivatives of AS. Even though the EEG of BA and IBIA change separately, they are followed by EEG of QS in a continuous pattern.
本研究的目的是通过自回归（AR）模型阐明足月儿和早产儿脑电图（EEG）背景活动随孕龄（CA）增加而发生的发育变化。从76名健康的足月儿和早产儿中获取多导EEG记录，其孕龄在31至40周之间。在安静睡眠（QS）的爆发活动（BA）期间以及主动睡眠（AS）期间，随着孕龄增加，δ波的总功率和成分功率下降。在QS的爆发间期活动（IBIA）期间，随着孕龄增加，δ波的总功率和成分功率增加。信息量（IA）的回归分析（RA）表明，在AS以及BA中的单极EEG描记Fp1、C3、O1和O2中，IA与孕龄增加呈负相关，而在IBIA中的O1中呈正相关。δ波IA的回归分析表明，在AS以及BA中的Fp1、C3、O1和O2中，IA与孕龄增加呈负相关，而在IBIA中的O1中呈正相关。δ波IA的回归分析表明，在BA和AS中，IA与孕龄增加呈负相关。这些结果表明，在AS中，随着发育，高电压慢波成分转变为低电压慢波成分，并且随着孕龄增加，BA持续时间更长、功率更低，而IBIA持续时间更短、功率更高。总之，AS的所有导数均发生显著的发育变化。尽管BA和IBIA的EEG分别变化，但它们以连续模式跟随QS的EEG变化。
