Okumura Akihisa, Kubota Tetsuo, Toyota Naoko, Kidokoro Hiroyuki, Maruyama Koichi, Kato Toru, Hayakawa Fumio, Watanabe Kazuyoshi
Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-Ku, Nagoya, Aichi 466-8550, Japan.
Brain Dev. 2003 Sep;25(6):406-10. doi: 10.1016/s0387-7604(03)00027-5.
The aim of this study is to clarify the usefulness of amplitude spectral analysis for an evaluation of maturational changes of delta activities in preterm infants. We chose each ten healthy infants without complications who were 29-30, 31-32, and 33-34 weeks of post-conceptional age (PCA) at electroencephalogram (EEG) recordings. Fast Fourier transform algorithm was applied for amplitude spectral analysis. The analyzed data were divided into four frequency bands; D1 0.53-1, D2 1-2, D3 2-3, and D4 3-4Hz. The average amplitude of six segments with high voltage slow waves was calculated in each frequency band. A significant reduction of the amplitude along with PCA was present in all leads in D1 band. On the other hand, a significant negative correlation with PCA was observed only in the occipital leads in D2, D3 or D4 bands. In conclusion, maturational EEG changes assessed by amplitude spectral analysis were prominent in the occipital areas, and in the frequency less than 1Hz.
本研究的目的是阐明振幅频谱分析在评估早产儿δ活动成熟变化方面的有用性。我们选择了在脑电图（EEG）记录时孕龄（PCA）分别为29 - 30周、31 - 32周和33 - 34周的10名无并发症的健康婴儿。采用快速傅里叶变换算法进行振幅频谱分析。分析的数据被分为四个频段：D1 0.53 - 1Hz、D2 1 - 2Hz、D3 2 - 3Hz和D4 3 - 4Hz。计算每个频段中六个高压慢波节段的平均振幅。D1频段所有导联中，振幅随PCA显著降低。另一方面，仅在D2、D3或D4频段的枕叶导联中观察到与PCA显著的负相关。总之，通过振幅频谱分析评估的EEG成熟变化在枕叶区域以及频率低于1Hz时最为显著。
