Yuzawa M, Tamakoshi A, Ueha M, Kawakubo H, Nakajima M
Department of Ophthalmology, Nihon University School of Medicine, Tokyo, Japan.
Ophthalmology. 1996 Dec;103(12):2037-41. doi: 10.1016/s0161-6420(96)30390-4.
To evaluate factors influencing visual acuity after laser photocoagulation for subfoveal choroidal neovascularization of exudative age-related macular degeneration.
Subfoveal choroidal neovascular membranes were photocoagulated. Factors favoring a visual acuity of 20/200 or better were analyzed using Fisher's exact probability test or chi-square test on 28 eyes in which visual acuity was 20/200 or better, and 23 eyes with a visual acuity below 20/200 at the most recent follow-up examination.
Factors predicting a postoperative visual acuity of 20/200 or better were (1) distance between one lateral margin of the neovascular membrane and the center of the foveal avascular zone was one-third disc diameter or less, and (2) pretreatment retinal sensitivity at the fixation point was 10 dB or more.
Good indications for photocoagulation treatment of subfoveal choroidal neovascular membrane were a neovascular membrane margin near the center of the foveal avascular zone and relatively good retinal sensitivity at the fixation point adjacent to the scotoma. These factors predict a visual acuity of 20/200 or better after treatment.
评估影响激光光凝治疗渗出性年龄相关性黄斑变性中心凹下脉络膜新生血管后视力的因素。
对中心凹下脉络膜新生血管膜进行光凝治疗。对28只末次随访时视力为20/200或更好的眼睛以及23只视力低于20/200的眼睛，采用Fisher精确概率检验或卡方检验分析有利于视力达到20/200或更好的因素。
预测术后视力为20/200或更好的因素为：（1）新生血管膜一侧边缘与中心凹无血管区中心的距离为三分之一视盘直径或更小；（2）注视点处治疗前视网膜敏感度为10 dB或更高。
中心凹下脉络膜新生血管膜光凝治疗的良好指征是新生血管膜边缘靠近中心凹无血管区中心，且在与暗点相邻的注视点处视网膜敏感度相对较好。这些因素可预测治疗后视力为20/200或更好。
