Knox-Macaulay H, Bhusnurmath S, Alwaily A
Department of Hematology, College of Medicine, Sultan Qaboos University, Muscat, Sultanate of Oman.
South Med J. 1997 Jan;90(1):69-71. doi: 10.1097/00007611-199701000-00016.
Gaucher-like cells were found in the bone marrow and liver of an Omani teenager who had common acute lymphoblastic leukemia (cALL) confirmed on peripheral blood analysis by the presence of CD10 antigen. Leukocytic or fibroblastic beta-glucocerebrosidase enzyme activity was not measured, but other biochemical data and features of bone marrow on electron microscopy were not indicative of genuine type 1 Gaucher's disease. To our knowledge, this is the first report of pseudo-Gaucher's cells in association with cALL.
在一名阿曼青少年的骨髓和肝脏中发现了类戈谢细胞，该青少年经外周血分析证实患有普通急性淋巴细胞白血病（cALL），外周血中存在CD10抗原。未检测白细胞或成纤维细胞的β-葡萄糖脑苷脂酶活性，但其他生化数据及骨髓在电子显微镜下的特征并不提示为真正的1型戈谢病。据我们所知，这是首例与cALL相关的假性戈谢细胞的报道。
