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[肝胆系统疾病中的脂质过氧化与血清过氧化物酶活性]

[Lipid peroxidation and blood serum peroxidase activity in diseases of the hepatobiliary system].

作者信息

Podil'chak M D, Vdovychenko V I, Terlets'ka L M

出版信息

Lik Sprava. 1996 Jan-Feb(1-2):110-2.

PMID:9005065
Abstract

Patients with hepatobiliary pathology showed an augmentation of peroxide oxidation of lipids (LP), its degree dependent upon the severity of the clinical course of the medical condition in question, being the highest in those patients with viral hepatitis, carcinoma of the head of pancreas, and portal cirrhosis of the liver. A parallel investigation into the blood serum peroxidase activity, the main indicator of the antioxidant activity, in the above patients, showed a noticeable decrease in PA activity. LP and blood serum PA measurements allow some judgement about the gravity of the course of hepatobiliary pathology and effectiveness of the therapy adopted.

摘要

患有肝胆疾病的患者脂质过氧化物氧化(LP)增加,其程度取决于所讨论疾病临床过程的严重程度,在病毒性肝炎、胰头癌和肝门脉性肝硬化患者中最高。对上述患者作为抗氧化活性主要指标的血清过氧化物酶活性进行的平行研究表明,PA活性显著降低。LP和血清PA测量有助于对肝胆疾病病程的严重程度和所采用治疗方法的有效性做出一些判断。

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