Boralevi F, Geniaux M
Service de dermatologie, Hôpital Pellegrin, Bordeaux.
Rev Prat. 1996 Oct 15;46(16):1952-60.
Herpes is the first cause of genital ulcers, recurrences are unpredictable and asymptomatic viral excretion is frequent. Herpes simplex virus 2 is responsible for genital infection in 80% of cases, but the incidence of Herpes simplex virus 1 is rising. New diagnostics methods are developing, batcellular viral culture remains gold standard. Oral aciclovir is the standard treatment, and directions for use are strictly codified. In pregnant women a new preventing project is proposed, it does not prevent transmission during asymptomatic viral excretion. In immunocompromise patients Herpes is frequent severe and sometimes aciclovir resistant.
疱疹是生殖器溃疡的首要病因,复发不可预测,且病毒无症状排泄很常见。单纯疱疹病毒2在80%的病例中导致生殖器感染,但单纯疱疹病毒1的发病率正在上升。新的诊断方法不断发展,而细胞培养仍然是金标准。口服阿昔洛韦是标准治疗方法,其使用说明有严格规范。对于孕妇,提出了一项新的预防方案,但它不能预防无症状病毒排泄期间的传播。在免疫功能低下的患者中,疱疹很常见且病情严重,有时对阿昔洛韦耐药。