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[切尔诺贝利事故辐射暴露成年人群的红细胞系统功能]

[Erythron system function in adults subjected to radiation exposure as a result of the Chernobyl accident].

作者信息

Bil'ko N M, Starodub N F, Bebeshko V G, Ternovoĭ K S

出版信息

Tsitol Genet. 1996 Jul-Aug;30(4):55-62.

PMID:9005638
Abstract

The morphofunctional state of hemopoiesis in patients who suffered from the Chernobyl accident was investigated. The activation of proliferative activity of erythroid progenitor cells simultaneously with a decrease in the resistance of erythrocytes and an increase in the levels of methemoglobin, HbF, and an increase in the number of HbF-containing cells in peripheral blood were detected. Main trends in the development of adaptative processes in the erythron system as a response to affect of low doses of radiation were determined on cellular and molecular levels.

摘要

对切尔诺贝利事故受害者造血的形态功能状态进行了研究。检测到红系祖细胞增殖活性激活,同时红细胞抵抗力下降,高铁血红蛋白、HbF水平升高,外周血中含HbF细胞数量增加。在细胞和分子水平上确定了红系系统适应性过程发展的主要趋势,作为对低剂量辐射影响的反应。

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