Pedley T A, Guilleminault C
Ann Neurol. 1977 Jul;2(1):30-5. doi: 10.1002/ana.410020105.
Six patients between the ages of 17 and 32 years presented with unusual sleep-walking epidodes characterized by screaming or unintelligible vocalizations; complex, often violent automatisms; and ambulation. Two or more attacks could occur in a single night and were most common in the early morning hours. Family and personal histories did not show epilepsy, psychiatric disorders, or (with 1 exception) previous somnambulism. Electrographic investigation revealed that all patients had normal waking-sleep cycles but that 4 of them had epileptiform abnormalities on their electroencephalograms. All patients were treated with either phenytoin or carbamazepine, with cessation of the abnormal nocturnal behavior during follow-up periods ranging from 9 to 48 months. This syndrome appears to be distinct from more typical non-rapid eye movement dyssomnias and suggests an atypical form of epilepsy.
6名年龄在17至32岁之间的患者出现了异常的梦游发作，其特征为尖叫或无法理解的发声、复杂且常伴有暴力行为的自动动作以及行走。一个晚上可能会发生两次或更多次发作，且最常发生在凌晨时分。家族史和个人史均未显示有癫痫、精神疾病或（有1例除外）既往梦游症。脑电图检查显示，所有患者的清醒-睡眠周期均正常，但其中4人的脑电图有癫痫样异常。所有患者均接受苯妥英或卡马西平治疗，在9至48个月的随访期内异常夜间行为停止。该综合征似乎有别于更典型的非快速眼动睡眠障碍，并提示一种非典型的癫痫形式。
