抑制来自携带HLA - B14个体的淋巴细胞混合白细胞培养反应性的人血T淋巴细胞。
Human blood T lymphocytes that suppress the mixed leukocyte culture reactivity of lymphocytes from HLA-B14 bearing individuals.
作者信息
Bean M A, Akiyama M, Kodera Y, Dupont B, Hansen J A
出版信息
J Immunol. 1979 Oct;123(4):1610-4.
PMID:90092
Abstract
A nontransfused male patient with recurrent bladder carcinomata has been demonstrated to have blood T lymphocytes that suppress the MLC responsiveness of lymphocytes only from normal individuals positive for HLA-B14. Unexpectedly, this T-suppressor cell differs from three other reported blood T-suppressor cells arising in man in that it apparently does not require HLA-D locus compatibility between the suppressor cell and the lymphocyte being suppressed.
摘要
一名患有复发性膀胱癌的未输血男性患者被证明其血液中的T淋巴细胞仅抑制来自HLA - B14阳性正常个体的淋巴细胞的混合淋巴细胞培养反应性。出乎意料的是，这种T抑制细胞与报道的另外三种人类血液中产生的T抑制细胞不同，因为它显然不需要抑制细胞与被抑制淋巴细胞之间的HLA - D位点相容性。
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