犬小孢子菌和库克小孢子菌蛋白水解酶的部分特性研究
Partial characterization of proteolytic enzymes of Microsporum canis and Microsporum cookei.
作者信息
Simpanya M F, Baxter M
机构信息
Department of Microbiology and Genetics, Massey University, Palmerston North, New Zealand.
出版信息
Mycoses. 1996 Jul-Aug;39(7-8):279-82. doi: 10.1111/j.1439-0507.1996.tb00138.x.
Characterization by proteinase inhibitors of the enzymes produced by Microsporum spp. revealed that Microsporum canis and Microsporum cookei produce serine proteinase(s), but only M. canis expresses aspartic and cysteine proteinases and probably a metalloproteinase. Both M. canis and M. cookei expressed metalloelastinolytic proteinases. All the proteinase types have been implicated in the pathogenicity of a wide range of microorganisms.
用蛋白酶抑制剂对小孢子菌属产生的酶进行特性分析发现，犬小孢子菌和库克小孢子菌可产生丝氨酸蛋白酶，但只有犬小孢子菌表达天冬氨酸蛋白酶和半胱氨酸蛋白酶，可能还表达一种金属蛋白酶。犬小孢子菌和库克小孢子菌均表达金属弹性蛋白酶。所有这些蛋白酶类型都与多种微生物的致病性有关。
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