Dipartimento di Sanità Pubblica e Zootecnia, Facoltà di Medicina Veterinaria, Università di Bari, Valenzano, Bari, Italy.
Mycoses. 2012 Jan;55(1):45-9. doi: 10.1111/j.1439-0507.2010.01997.x. Epub 2011 Oct 3.
Microsporum canis and Trichophyton mentagrophytes are zoophilic dermatophytes which can cause skin infections in animals and humans. The clinical expression of this infection strongly varies depending on host, fungal species as well as enzyme production. No comparative studies are available on the enzymatic activities of M. canis and T. mentagrophytes isolated from breeding rabbits. Thus, the aim of this work was to assess the capability of M. canis and T. mentagrophytes isolated from rabbits both with and without lesions in producing different enzymes. The relationship of dermatophyte enzymatic activities and presence/absence of skin lesions has also been investigated. A total of 260 isolates of T. mentagrophytes and 25 isolates of M. canis sampled both from healthy and lesioned skin of rabbits, as well as from air samples of positive farms were examined. The results showed that T. mentagrophytes and M. canis from rabbits produce different enzymes. However, only elastase and gelatinase were linked to the appearance of lesions in T. mentagrophytes infections, whereas lipase in those by M. canis.
犬小孢子菌和须癣毛癣菌是亲动物性皮肤癣菌，可引起动物和人类的皮肤感染。这种感染的临床表现因宿主、真菌种类以及酶的产生而有很大差异。目前尚无关于从繁殖兔中分离出的犬小孢子菌和须癣毛癣菌的酶活性的比较研究。因此，本研究旨在评估来自有和无病变的兔子的犬小孢子菌和须癣毛癣菌产生不同酶的能力。还研究了皮肤癣菌酶活性与皮肤损伤的存在/不存在之间的关系。共检查了 260 株须癣毛癣菌和 25 株来自健康和有病变兔皮肤以及阳性农场空气样本的犬小孢子菌。结果表明，来自兔子的须癣毛癣菌和犬小孢子菌产生不同的酶。然而，只有弹性蛋白酶和明胶酶与须癣毛癣菌感染中出现的病变有关，而犬小孢子菌的脂酶则与病变有关。
