Sostre S, Handler H L
Arch Dermatol. 1977 Sep;113(9):1245-7.
Bone, bone marrow and gallium citrate Ga 67 scans were performed on a patient with systemic mastocytosis and bony involvement to evaluate their diagnostic value in such patients. The bone scan revealed increased tracer concentration in the involved areas. These abnormalities were less prominent than those on the roentgenograms, suggesting that only a part of the roentgenographic abnormalities were associated with reactive bone formation. Bone scanning may be less sensitive than roentgenograms to detect the full extent of the bony lesions of systemic mastocytosis. The bone marrow scan revealed a normal central marrow with peripheral marrow expansion. Possibly, the central marrow infiltration by mast cells was sufficient to interfere with its hemopoietic function to a degree that made it necessary to reactivate peripheral marrow tissue. There was no significant 67Ga accumulation in the bony lesions of systemic mastocytosis.
对一名患有系统性肥大细胞增多症并伴有骨受累的患者进行了骨骼、骨髓和枸橼酸镓Ga 67扫描，以评估它们在此类患者中的诊断价值。骨扫描显示受累区域的示踪剂浓度增加。这些异常不如X线片上的明显，表明只有部分X线异常与反应性骨形成有关。骨扫描在检测系统性肥大细胞增多症骨病变的全部范围方面可能不如X线片敏感。骨髓扫描显示中央骨髓正常，外周骨髓扩张。可能肥大细胞对中央骨髓的浸润足以在一定程度上干扰其造血功能，从而有必要重新激活外周骨髓组织。系统性肥大细胞增多症的骨病变中没有明显的67Ga积聚。
