Tsambaos D, Orfanos C E
Arch Dermatol Res (1975). 1977 Jul 21;259(1):97-100. doi: 10.1007/BF00562742.
In 64 patients with psoriasis and in 54 persons without any skin disease the amount of zinc was estimated in plasma and in the erythrocytes using atomic absorption spectrophotometry. The findings showed an elevated plasma level and a lower zinc content of blood erythrocytes in psoriasis. Both values were statistically significant. No relation was found between these changes and the percentage skin surface covered by psoriatic lesions. The disturbed distribution of zinc in psoriasis may be due to disturbances if histidine metabolism or to changes of the permeability of the cell membranes associated with this skin disease.
对64例银屑病患者和54例无任何皮肤疾病的人,采用原子吸收分光光度法测定血浆和红细胞中的锌含量。结果显示,银屑病患者血浆锌水平升高,红细胞锌含量降低。这两个值均具有统计学意义。未发现这些变化与银屑病皮损覆盖的皮肤表面积百分比之间存在关联。银屑病中锌分布紊乱可能是由于组氨酸代谢紊乱或与该皮肤病相关的细胞膜通透性改变所致。