Cremer P D, Johnston I H, Halmagyi G M
Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, Australia.
J Neurol Neurosurg Psychiatry. 1997 Jan;62(1):96-8. doi: 10.1136/jnnp.62.1.96.
Three cases are reported of the pseudotumour cerebri syndrome-that is, intracranial hypertension without mass lesion or enlarged ventricles, due to cryptococcal meningitis. In these patients the papilloedema was successfully treated with optic nerve sheath decompression, and the intracranial hypertension with lumboperitoneal CSF shunting. These cases support the concept that pseudotumour cerebri is a syndrome of intracranial hypertension that can be due to any disorder producing obstruction of the CSF pathways at the level of the arachnoid villi. This concept is important because it directs therapy to normalise the intracranial pressure and preserve vision.
本文报告了3例假性脑瘤综合征病例,即由隐球菌性脑膜炎引起的无占位性病变或脑室扩大的颅内高压。在这些患者中,视神经鞘减压成功治疗了视乳头水肿,腰大池-腹腔脑脊液分流术治疗了颅内高压。这些病例支持了假性脑瘤是一种颅内高压综合征的概念,其可由任何导致蛛网膜绒毛水平脑脊液通路阻塞的疾病引起。这一概念很重要,因为它指导治疗以将颅内压恢复正常并保护视力。