Tan C T
Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
J Neurol Neurosurg Psychiatry. 1988 Jul;51(7):944-6. doi: 10.1136/jnnp.51.7.944.
Thirty four patients with cryptococcal meningitis seen in the University of Malaya medical centre since 1980 were reviewed. Eleven patients had bilateral papilloedema and visual impairment but eventually survived. Seven patients had intensive aggressive measures, including shunting to reduce intracranial hypertension irrespective of ventricular size shown in CT scan, and showed substantial improvement in vision. It is concluded that papilloedema and visual failure in cryptococcal meningitis reflects raised intracranial pressure and that this should be treated vigorously.
对1980年以来在马来亚大学医学中心就诊的34例隐球菌性脑膜炎患者进行了回顾性研究。11例患者出现双侧视乳头水肿和视力损害,但最终存活。7例患者采取了积极的强化治疗措施,包括无论CT扫描显示脑室大小如何均进行分流以降低颅内压,视力有显著改善。结论是隐球菌性脑膜炎中的视乳头水肿和视力减退反映了颅内压升高,对此应积极治疗。