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[食物在特应性皮炎中的作用]

[Role of food in atopic eczema].

作者信息

Dotterud L K

机构信息

Hudavdelingen, Regionsykehuset i Trondheim.

出版信息

Tidsskr Nor Laegeforen. 1996 Nov 20;116(28):3335-40.

PMID:9011990
Abstract

Some new aspects of adverse reactions to food are reviewed. People quite often blame food for the development of allergic symptoms. These true reactions can be divided into three groups: Immunological (food allergy--type I-IV reactions), non-immunological (intolerance--result of non-immunologic mechanisms) and toxic/biochemical reactions. The patterns of adverse food reactions are age dependent, especially allergy to cow's milk, hen's egg-white and soya, and symptoms appear most frequently in children under three years of age. 10-20% of children report adverse reactions to food, but only 3-5% have IgE-mediated reactions. In children with moderate to severe atopic dermatitis as many as 30% are reported to have food allergies. In adults, it is believed that 3-12% may have some kind of adverse reaction to specific foods, but only 1-2% have food allergy. The most common symptoms of adverse food reactions appear in the skin and in the gastrointestinal tract, but respiratory symptoms are also observed. Once food allergy has been proven conclusively the identified food should be totally eliminated from the diet. If important foods are eliminated the patient's sensitivity should be reevaluated again after a time.

摘要

本文综述了食物不良反应的一些新情况。人们常常将过敏症状的出现归咎于食物。这些真正的反应可分为三类:免疫性(食物过敏——I-IV型反应)、非免疫性(不耐受——非免疫机制的结果)和毒性/生化反应。食物不良反应的模式与年龄有关,尤其是对牛奶、蛋清和大豆的过敏,症状最常出现在三岁以下的儿童中。10%-20%的儿童报告有食物不良反应,但只有3%-5%有IgE介导的反应。据报道,患有中度至重度特应性皮炎的儿童中,多达30%有食物过敏。在成年人中,据信3%-12%可能对特定食物有某种不良反应,但只有1%-2%有食物过敏。食物不良反应最常见的症状出现在皮肤和胃肠道,但也观察到呼吸道症状。一旦食物过敏得到确凿证实,应从饮食中完全剔除已确定的食物。如果剔除了重要食物,一段时间后应再次重新评估患者的敏感性。

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