Omel'ianenko N P, Zherebtsov L D, Mikhaĭlov I N
Arkh Anat Gistol Embriol. 1977 Apr;72(4):69-76.
Histological and histochemical methods and fluorescent and rastral electron microscopy were used for complex investigation of intercellular connective tissue components of the human skin derm (collagenous and elastin fibres, basic substance). The structure of collagenous fibres in different levels of their organization was studied. The structure of periods and differently directed combination of fibrils in the fibre were revealed by different methods. Five types of ruthenies--positive structures in the basic substance and fibres--were found. A supposition is made and substantiated that two interconnected and diverse mechanisms take part in sustaining the structure--function integrity of the collagenous fibre. One of them prevents from rapprochement of fibrils (different direction of fibres, amorphous substance) and the other connect them (adhesive properties of the amorphous substance).
采用组织学、组织化学方法以及荧光和扫描电子显微镜对人体皮肤真皮的细胞间结缔组织成分（胶原纤维和弹性纤维、基质）进行综合研究。研究了胶原纤维在不同组织水平的结构。通过不同方法揭示了纤维中周期结构以及原纤维不同方向的组合。在基质和纤维中发现了五种钌红阳性结构。提出并证实了一种假设，即两种相互关联且不同的机制参与维持胶原纤维的结构 - 功能完整性。其中一种机制防止原纤维相互靠近（纤维方向不同、无定形物质），另一种机制则将它们连接起来（无定形物质的黏附特性）。
