Veien K, Veien N K, Hattel T, Laurberg G
Hudklinikken, Aalborg.
Ugeskr Laeger. 1996 Dec 9;158(50):7213-5.
The study was carried out to determine the results of treatment of a cohort of patients with histologically verified non-melanoma skin cancer diagnosed and followed prospectively for two years in a private practice of dermatology. Throughout the follow-up period, any new non-melanoma skin cancers among this cohort were recorded. Six hundred and forty-six consecutive patients seen in the Dermatology Clinic, Vesterbro 99, Aalborg, Denmark, from July 1, 1990, to June 30, 1993, had a total of 768 tumours that were histologically verified as basal cell carcinoma, squamous cell carcinoma or Bowen's disease. Six hundred and twenty-eight tumours in 526 patients were treated in our clinic, 91% of these with curettage followed by electrocautery. Hundred and twenty patients with a total of 140 tumours were referred to a local hospital for treatment. Thirty-six of the 508 basal cell carcinomas treated in the clinic recurred during the follow-up period, and one mixed tumour (basal cell and squamous cell carcinoma) recurred. During the follow-up period, 151 new non-melanoma skin cancers were detected. In addition, 10 patients each developed 10 or more new tumours.
本研究旨在确定一组经组织学证实的非黑色素瘤皮肤癌患者的治疗结果,这些患者在一家皮肤科私人诊所被诊断并前瞻性随访了两年。在整个随访期间,记录了该队列中任何新的非黑色素瘤皮肤癌病例。1990年7月1日至1993年6月30日期间,在丹麦奥尔堡韦斯特布罗99号皮肤科诊所连续就诊的646例患者,共有768个肿瘤经组织学证实为基底细胞癌、鳞状细胞癌或鲍温病。526例患者的628个肿瘤在我们诊所接受了治疗,其中91%采用刮除术加电灼术治疗。120例患者共140个肿瘤被转诊至当地医院治疗。在诊所接受治疗的508例基底细胞癌中,有36例在随访期间复发,1例混合性肿瘤(基底细胞癌和鳞状细胞癌)复发。在随访期间,检测到151例新的非黑色素瘤皮肤癌。此外,10例患者各自长出了10个或更多的新肿瘤。