Stepansky R, Weber G, Zeitlhofer J
Universitätsklinik für Neurologie, Wien.
Wien Med Wochenschr. 1996;146(9-10):209-10.
19 middle-aged patients with myasthenia gravis (MG) and 10 age-matched controls underwent overnight polysomnography and neuropsychological testing, in order to assess the frequency, degree, type and risk factors of sleep apneas in MG and to show their influence on sleep profile and neuropsychological variables. We observed in 60% of the myasthenics, low grade central type of sleep apneas and hypopneas with resulting oxygen desaturations, occasionally occurring during REM-sleep without influence on sleep profile and vigilance but resulting in significant memory impairment. The only found risk factor for the development of sleep apneas was age.
19名中年重症肌无力(MG)患者和10名年龄匹配的对照者接受了夜间多导睡眠图和神经心理学测试,以评估MG患者睡眠呼吸暂停的频率、程度、类型和危险因素,并显示其对睡眠特征和神经心理学变量的影响。我们在60%的肌无力患者中观察到,存在轻度中枢型睡眠呼吸暂停和呼吸浅慢,伴有氧饱和度下降,偶尔发生在快速眼动睡眠期,对睡眠特征和警觉性无影响,但导致明显的记忆损害。发现的睡眠呼吸暂停发生的唯一危险因素是年龄。