Lloyd W E, Paty P S, Darling R C, Chang B B, Fitzgerald K M, Leather R P, Shah D M
Vascular Surgery Section, Albany Medical College, New York 12208, USA.
Cardiovasc Surg. 1996 Dec;4(6):724-6. doi: 10.1016/s0967-2109(96)00031-2.
In order to identify major risks for death and complications from elective repair of abdominal aortic aneurysm, the authors analyzed their experience with the last 1000 such repairs over a 15-year period. Of the patients, 772 were men and 228 were women; average age was 70 (range 37-92) years. Some 20% of the patients had severe chronic obstructive pulmonary disease and 33% had baseline creatinine level > 115 mumol/l. Fifteen patients were dialysis-dependent and 24% (242/1000) had significant cardiac disease. Operation used a retroperitoneal approach in 834 patients and a transperitoneal approach in 166. The perioperative mortality rate was 2.4%, but this did not change either chronologically or with technique: some 50% of the deaths were due to cardiac causes. Renal and pulmonary impairment did not affect mortality or complication; 64% of non-fatal complications were distributed in the renal (17%), pulmonary (19%) and cardiac groups (28%). The authors' experience showed that patients with cardiac disease remain at significant risk for post-abdominal aortic aneurysm repair complications in spite of selective preoperative cardiac evaluation. Renal and pulmonary risk factors did not cause additional mortality or morbidity. They suggest that elective abdominal aortic aneurysm repair can be performed with low mortality and morbidity, even in increasing numbers of high-risk patients.
为了确定择期腹主动脉瘤修复术的主要死亡风险和并发症,作者分析了他们在15年期间进行的最后1000例此类修复手术的经验。患者中,772例为男性,228例为女性;平均年龄为70岁(范围37 - 92岁)。约20%的患者患有严重的慢性阻塞性肺疾病,33%的患者基线肌酐水平>115μmol/L。15例患者依赖透析,24%(242/1000)患有严重心脏病。834例患者手术采用腹膜后入路,166例采用经腹入路。围手术期死亡率为2.4%,但这在时间上或技术上均未发生变化:约50%的死亡是由心脏原因导致的。肾脏和肺部功能损害并未影响死亡率或并发症;64%的非致命并发症分布在肾脏(17%)、肺部(19%)和心脏组(28%)。作者的经验表明,尽管进行了选择性术前心脏评估,但患有心脏病的患者腹主动脉瘤修复术后仍面临显著的并发症风险。肾脏和肺部风险因素并未导致额外的死亡率或发病率。他们认为,即使高危患者数量不断增加,择期腹主动脉瘤修复术仍可在低死亡率和低发病率的情况下进行。